Minocycline-Induced Hyperpigmentation Resolves during Oral Isotretinoin Therapy
December 2007 | Volume 6 | Issue 12 | 1232 | Copyright © December 2007
Jennifer Soung MD, Justine Cohen BA, Robert Phelps MD, Steven R. Cohen MD MPH
Abstract
Although disfiguring hyperpigmentation is a well-defined complication of minocycline therapy, modalities to reverse the
phenomenon are unpredictable. We report a case of minocycline-induced, blue-black pigmentation in a 23-year-old Hispanic
man, which resolved after treatment with oral isotretinoin for acne vulgaris. 
