JDD Corner

JDD Corner

Welcome to JDD Corner, your gateway to a world of dermatology knowledge and insights! JDD Corner is a curated collection of video abstracts, editor picks, Key Opinion Leader (KOL) spotlights, trending articles, and much more. Whether you are a dermatologist, a skincare enthusiast, or simply curious about the latest advancements in dermatology, JDD Corner is your one-stop destination for staying informed and up-to-date with the most exciting developments in the field. Explore our carefully selected content and immerse yourself in the dynamic world of dermatology. Welcome to JDD Corner!

Video Abstracts

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NEW! VIDEO ABSTRACT

Acetyl Dipeptide-31 Amide: A Novel Cosmetic Anti-Inflammatory Peptide That Demonstrates Anti-Aging, Firming, and Lifting Benefits

 There is continuous demand for safe, effective cosmetic ingredients to treat the signs of aging skin, including fine lines, wrinkles, brown spots, discoloration, laxity, and sagging. While there are a plethora of cosmeceutical peptides, few combine anti-aging and anti-inflammatory benefits with small size.

NEW! VIDEO ABSTRACT

GLP-1 Receptor Agonists for the Dermatologist: Uses and Considerations

The glucagon-like peptide-1 receptor agonists (GLP1RAs) are a widely popularized drug class due to their notable success in promoting weight loss. The GLP1RAs, dulaglutide, exenatide, semaglutide, liraglutide, tirzepatide, and lixisenatide are FDAapproved for use in the treatment of obesity and type 2 diabetes mellitus (DM), particularly to reduce cardiovascular risk and improve glycemic control.1,2,3 GLP1RAs work by mimicking glucagon-like peptide-1 (GLP-1), an incretin, that functions to subdue appetite, delay gastric emptying, and regulate homeostasis of glucose.

NEW! VIDEO ABSTRACT

New Formulations of Acyclothymidine Dinucleosides Reduce Damaging Effects of Ultraviolet Radiation in an Ex Vivo Skin Model

The greatest risk factor for skin cancer is exposure to ultraviolet (UV) rays of the sun. Among the three types of solar radiation (UVA, UVB, UVC), UVB rays are most commonly associated with skin cancer. UVB exposure promotes the formation of cyclobutane pyrimidine dimers (CPDs) in the DNA of cells in the epidermal skin layers, which can lead to mutations as DNA repair machinery attempts to repair the damage. 

NEW! VIDEO ABSTRACT

Assessment of the Vehicle for Roflumilast Cream Compared to a Ceramide-Containing Moisturizing Cream in Mild Eczema

The role of the vehicle in topical prescription treatments is to deliver therapeutic concentrations of an active drug to a designated skin target site to support patient adherence and satisfaction, ideally without skin irritation. To achieve a pharmacological effect, the drug must be able to penetrate through the stratum corneum (SC) into the viable epidermis and dermis. The skin barrier is composed of terminally differentiated keratinocyte cells (corneocytes) and lipid lamellae, which prevent the movement of water out of the skin.

VIDEO ABSTRACT

Structural Insights: What Makes Some IL-23 Biologics More Effective in Psoriasis

Understanding IL-23 Biologics
IL-23 biologics are designed to bind to specific regions (epitopes) on the p19 or p40 subunits, preventing IL-23 from activating its receptor and triggering the inflammatory cascade responsible for psoriasis. 

VIDEO ABSTRACT

Pathophysiologic Targets for Acne Treatment

Acne vulgaris is an extremely common dermatologic condition. Individuals with acne present not only to dermatologists, but also to internists, family medicine physicians, pediatricians, estheticians, and beauty counters alike in search of a treatment. The diagnosis of acne is relatively straightforward, leading many to believe that acne is a simple condition.

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Author Spotlight

Deborah S. Sarnoff MD
JDD Editor-in-Chief

The Journal of Drugs in Dermatology is proud to announce Deborah S. Sarnoff MD as our new Editor-in-Chief. Please check out her first announcement of all the latest updates at JDD. 

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Trending Articles

Artificial Intelligence-Based Personalization of Treatment Regimen for Hair Loss: A 6-Month Clinical Trial

Hair loss affects up to 50% of women and 80% of men. The high costs and wait times for professional consultations lead many to seek one-size-fits-all solutions that are frequently ineffective. 

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The Multifaceted Effects of Berberine: Potential Uses in Dermatology

Berberine is a natural alkaloid found in several plant species and has been utilized in traditional medicine for its antimicrobial, anti-inflammatory, and antioxidant properties. 

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Social Media’s Impact on Hair Loss Information Dissemination: A Systematic Review

This systematic study examines the quality of hair loss information disseminated on social media platforms, as well as its potential effects on users’ decision-making, emotional states, and societal attitudes toward hair loss.

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The Use of Acneceuticals to Improve Acne Care: Introduction of a New Term and Review of the Literature

Acne is a multifactorial inflammatory skin condition that commonly presents to the dermatology clinic. Treatment generally involves the use of pharmaceutical agents and procedural techniques.

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Effects on the Skin Microbiome by a Moisturizer Formulated for Eczema-Prone and Sensitive Skin

Cutaneous dysbiosis contributes to the pathophysiology of atopic dermatitis and potentially that of sensitive skin; regulation of the bacterial communities through skincare products is an emerging management strategy. 

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The Potential Risk of Povidone-Iodine in Sperm Quality: A Case Report

To report a rare case of severe oligoasthenoteratozoospermia which seems to be associated with long-term topical povidone-iodine (PVP-I) therapy. A 45-year-old man with secondary infertility was diagnosed with mild asthenospermia before undergoing in vitro fertilization (IVF). 

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Recent News

Editor's Picks

March 4, 2025

Keeping You at the Forefront

March 3, 2025

Social Media’s Impact on Hair Loss Information Dissemination: A Systematic Review

Exosomes in Cosmetic Dermatology: A Review of Benefits and Challenges 

Video Pearls

Tough Day at the Office: Lupus, Sarcoidosis, and a Side of Morphea

Watch as Dr. Friedman shares basic principles to managing three distinct diseases – cutaneous lupus, sarcoidosis and linear morphea. Learn why you need to do a good review of organ systems and be prepared to phone a friend (or more) across the aisle in medicine.

Tips for Providing Better Atopic Dermatitis Care

With the growing list of therapeutic options, Dr. Friedman encourages clinicians to go back to the basics and address one of the greatest challenges — treatment adherence.

Acne and Diet

Adam Friedman, professor and chair of dermatology at GW School of Medicine and Health Sciences. Dr. Friedman says acne is an evidence-based example of the saying “you are what you eat.”

Crushing It In The Capital: Lessons From Residency Translated

Dr. Friedman provides his tips for remaining calm during the craziest of office visits. He also shares why being fun, creative and an off-label bandit matters. 

New Innovations in Hyperpigmentation

Dr. Chilukuri outlines at-home and in-office treatments to address hyperpigmentation, including newly developed therapies.