Issue Archive
September 2010 | Volume 9 | Issue 9
Original Articles
Correction of Atrophic Scars With Artefill: An Open-label Pilot Study
Background: Artefill®, a novel permanent filler approved by the U.S. Food and Drug Administration (FDA), has been used as an injectable implant for the correction of nasolabial folds. Fillers are ...
Read MoreClinical Trial Review
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs undergoing clinical testing. It is our goal to inform the reader of the status of select drug trials ...
Read MoreCurrent and Future Botulinum Neurotoxin Type A Preparations in Aesthetics: A Literature Review
Botulinum neurotoxin type A (BTX-A) preparations are well established for cosmetic use. BTX-A inhibits the release of acetylcholine, resulting in temporary muscle paralysis, which has been utilized s...
Read MorePipeline Previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatological community. This department may include additional information from t...
Read MoreHistopathologic Identification of Dermal Filler Agents
As reflected in the literature, the use of dermal filler agents has increased substantially over the last decade. Consequently, these agents are more frequently encountered on histopathologic examina...
Read MoreRetrospective Review of 500 Patients Treated With AbobotulinumtoxinA
Background: Prior international clinical experience and domestic controlled clinical trials provide useful guidance for dosing of a new botulinum toxin type A, abobotulinumtoxinA. Nonetheless, afterm...
Read MoreFormulation Composition of Botulinum Toxins in Clinical Use
The use of botulinum toxin (BoNT) has now become the treatment of choice for a range of debilitating neuromuscular diseases and for aesthetic medicine. BoNT products are licensed as prescription-only...
Read MoreFailure of Botulinum Toxin Treatment for Localized Vitiligo
Background: It was found that acetylcholine concentration increased with a significantly reduced expression of acetylcholinesterase in vitiliginous patches that return to normal upon repigmentation. ...
Read MoreThe Effect of Lidocaine When Mixed with Large Gel Particle HyaluronicAcid Filler on Tolerability and Longevity: A Six-month Trial
Objectives: To determine if there is any effect on tolerance, adverse events or clinical outcome when lidocaine is added to large gel particle hyaluronic acid (LGP-HA). Materials and Methods: Single...
Read MoreA Randomized, Double-blinded, Placebo-controlled, Multicenter, Efficacy and Safety Study of 3.75% Imiquimod Cream Following Cryosurgery for the Treatment of Actinic Keratoses
Objective: Evaluate cryosurgery followed by 3.75% imiquimod cream to treat actinic keratoses (AK). Methods: Adults with ≥10 AKs on the face underwent cryosurgery of five to 14 lesions. Subjects...
Read MoreOnychomycosis Therapy: Past, Present, Future
Methods to treat onychomycosis are varied, using therapies that can be categorized as topical, oral or device-related. Since their development, oral therapies have represented the gold standard for t...
Read MoreMechanism of Action and Clinical Benefits of Colloidal Oatmeal for Dermatologic Practice
Colloidal oatmeal has a long history of beneficial use in dermatology. It is a natural product that has an excellent safety record and has demonstrated efficacy for the treatment of atopic dermatitis,...
Read MoreClinical Efficacy of a Novel Sonic Infusion System for Periorbital Rhytides
Aging skin is a leading concern of most men and women seeking cosmetic dermatologic consultation. Various in-office procedures as well as topical at-home regimens, are generally prescribed to reduce ...
Read MoreReview of Actinic Keratosis. Part I:Etiology, Epidemiology and Clinical Presentation
Clinically, actinic keratoses (solar keratoses) are keratotic lesions that occur on chronically sunlight-exposed skin. Histologically, they are epidermal tumors. Presenting with a spectrum of clinica...
Read MoreHyaluronic Acid Filler and Botulinum Neurotoxin Delivered Simultaneously in the Same Syringe for Effective and Convenient Combination Aesthetic Rejuvenation Therapy
Facial aesthetics and rejuvenation techniques have been evolving, with the most commonly applied techniques being the use of hyaluronic acid fillers and botulinum neurotoxins. Because of complementar...
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Features
Case Reports
Urticarial Hypersensitivity Reaction Caused by Temozolomide
Temozolomide is an oral alkylating agent approved for the treatment of glioblastoma and anaplastic astrocytoma, and is currently under clinical investigation for the treatment of brain metastases fro...
Read MoreSubcutaneous Fat Necrosis/Panniculitis and Polyarthritis Associated With Acinar Cell Carcinoma of the Pancreas: A Rare Presentation ofPancreatitis, Panniculitis and Polyarthritis Syndrome
An 82-year-old man presented with a two-week history of three painful, inflamed nodules on his lower extremities with symmetric arthritis of multiple joints. He was under the care of hospice for end-...
Read MorePalliative Treatment of Paraneoplastic Acanthosis Nigricans With Oral Florid Papillomatosis With Retinoids
Malignant acanthosis nigricans (MAN) with oral florid papillomatosis is a rare paraneoplastic condition affecting the skin and mucocutaneous tissues associated with an underlying malignancy. It is ch...
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