Issue Archive
June 2010 | Volume 9 | Issue 6
Editorials
Optimizing Patient Adherence: Update onCombination Acne Therapy—Teens and Beyond
Acne vulgaris can cause both physical and emotional scarring. Effective treatment requires an understanding of acne pathogenesis and the key elements of keratinocyte differentiation and comedone forma...
Read MoreInnovations in Natural Ingredients andTheir Use in Skin Care
Natural ingredients have been used traditionally for millennia and their application in topical creams, lotions and preparations within the traditional medicines and healing traditions of many culture...
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Original Articles
Pimecrolimus 1% Cream in the Treatment of Cutaneous Lesions of Pemphigus Vulgaris: A Double-blind, Placebo-controlled Clinical Trial
Background: Pemphigus vulgaris (PV) is a chronic, bullous disorder that is usually characterized by the presence of bulla and erosion on the skin and mucosa. Many studies on PV focus on the use of to...
Read MoreEfficacy of Topical Azelaic Acid (AzA) Gel 15% Plus Oral Doxycycline 40 mg Versus Metronidazole Gel 1% Plus Oral Doxycycline 40 mg in Mild-to-Moderate Papulopustular Rosacea
Rosacea is a leading reason why people seek the care of a dermatologist, accounting for nearly 7 million office visits annually. Pharmacologic treatments include both topical and oral medications, wh...
Read MoreLaser and Light-based Therapies for Acne Vulgaris:A Current Guide Based on Available Data
There are some patients that, despite their continued use of optimized topical and systemic medication and skin care regimens, exhibit at least partial persistence of acne vulgaris (AV) lesions that ...
Read MoreEfficacy of Benzoyl Peroxide (5.3%) Emollient Foam and Benzoyl Peroxide (8%) Wash in Reducing Propionibacterium acnes on the Back
Background: Topical treatment of acne vulgaris on the back is challenging largely due to the extensive broad surface with difficult to reach areas. A “leave-on” foam is suited for applicat...
Read MoreA Status Report On Drug-associated Acne and Acneiform Eruptions
Several drugs have been associated with the development of eruptions that may simulate acne vulgaris. These drugs include corticosteroids, epidermal growth factor receptor inhibitors, cyclosporine, a...
Read MoreNews, Views & Reviews
Iron levels are tightly regulated in the body to maintain homeostasis. When homeostatic mechanisms malfunction, excess iron accumulation in the body has deleterious effects with important health con...
Read MoreAdapalene 0.1% Lotion in the Treatment of Acne Vulgaris: Results From Two Placebo-controlled, Multicenter, Randomized Double-blind, Clinical Studies
Background: Acne vulgaris is a common chronic skin disease affecting roughly 15 percent of the general population and up to 85 percent of adolescents and young adults. Adapalene, a synthetic naphthoi...
Read MorePipeline previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatological community. This department may include additional information from ...
Read MoreLong-term Efficacy and Safety of TopicalPRK 124 (0.125%) Lotion (Pyratine-XR) in theTreatment of Mild-to-Moderate Rosacea
Background: Many patients with rosacea cannot tolerate extended treatment periods with topical agents because their skin sensitivity is often increased. Objective: To determine the long-term efficac...
Read MoreResident Rounds
Winning Poster: Body Image Disturbance in Patients With Acne Vulgaris...
Read MoreThe Development of Antimicrobial Resistance Due to the Antibiotic Treatment of Acne Vulgaris: A Review
Objective: To review recent studies on the use of antibiotics in acne vulgaris which provide insight into the development of antimicrobial resistance. Data sources: Sources for this article were ide...
Read MoreClinical Trial Review
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs undergoing clinical testing. It is our goal to inform the reader of the status of select drug trials ...
Read MoreHarnessing the Anti-inflammatory Effects of Topical Dapsone for Management of Acne
Data continue to establish the role of inflammation, not only in the pathogenesis of acne but also in the development of its most devastating sequelum, scarring. Although topical therapy is preferred...
Read MoreVertical Undermining for the Closure of PartialThickness Surgical Defects
Vertical undermining for repair of partial thickness defects is a new effective technique that allows the wound edges of partial thickness defects to be freed and mobilized so that they can be repair...
Read MoreEffects of Ustekinumab Administration on Primate/Human Antigen-recall and Humoral Immune Response Functions
Background: Ustekinumab, a fully human immunoglobulin (Ig) G1κ monoclonal antibody directed against the p40 subunit of interleukin (IL)-12/23, has demonstrated efficacy in patients with moderate...
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Features
Case Reports
ALA -PDT for the Treatment of Cutaneous Pseudolymphoma: A Case Report
Cutaneous pseudolymphoma (CPL) is a benign skin condition that may cause cosmetic disfigurement, severe itch and, albeit rarely, transformation to malignant lymphoma. The usual treatment modalities f...
Read MoreMonophasic, Cohesive-polydensified-matrixCrosslinking-technology-based Hyaluronic AcidFiller for the Treatment of Facial Lipoatrophyin HIV-infected Patients
Human immunodeficiency virus (HIV)-associated facial lipoatrophy (FLA) represents a common and highly stigmatizing side effect of retroviral therapy. By causing loss of subcutaneous adipose tissue ma...
Read MoreAnnular Leukocytoclastic Vasculitis Associated With Sorafenib Administration
Only one case of vasculitis associated with sorafenib has been reported, and the authors now present the first reported case of annular leukocytoclastic vasculitis (LCV) linked to sorafenib administr...
Read MoreIsotretinoin as Monotherapy for Sebaceous Hyperplasia
Sebaceous hyperplasia is a common benign lesion composed of sebaceous glands. It is characterized as yellow or flesh-toned papules with central umbilication. The authors report the case of a 57-year-...
Read MoreRapid Improvement of Pyoderma Gangrenosum After Treatment With Infliximab
Infliximab, a novel chimeric anti-tumor necrosis factor-α (TNF-α) monoclonal antibody, has been increasingly used in the treatment of pyoderma gangrenosum. However, an established dosing re...
Read MoreA Case Report of Postpubertal Eruptive Syringoma Triggered With Antiepileptic Drugs
Eruptive syringoma is a rare variant of syringoma, which typically occurs in large numbers as multiple yellow-brown colored papules. It usually presents before or during puberty. The pathogenesis of ...
Read MoreSuccess of Oxandrelone in the Treatment of Decubitus Ulcers
A case of pressure ulcer in a 25-year-old male patient with the neurodegenerative disorder giant axonal neuropathy (GAN) was safely and effectively treated with an eight-week regimen of oxandrolone a...
Read MoreRapid Improvement in Digital Ischemia and AcralContracture in a Collodion Baby Treated With Topical Tazarotene
Collodion baby is a rare congenital disorder whereby affected infants are born encased in a thick, taut, shiny, translucent membrane. The majority of babies with collodion membrane have associated di...
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