Issue Archive
May 2010 | Volume 9 | Issue 5
Editorials
Scientific Proceedings FromSelect Sessions at the2010 Orlando DermatologyAesthetic & Clinical (ODAC) Conference
This supplement to the Journal of Drugs in Dermatology is supported by Graceway Pharmaceuticals, LLC, Ortho Dermatologics, Inc., Osyris and The Procter & Gamble Company...
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Original Articles
Randomized Comparison of the Safety and Efficacy of Tazarotene 0.1% Cream andAdapalene 0.3% Gel in the Treatment of Patients With at Least Moderate FacialAcne Vulgaris
This 16-week study evaluated once-daily tazarotene 0.1% cream and adapalene 0.3% gel in patients with moderate-to-severe acne. Patients treated with tazarotene 0.1% cream performed better in many acn...
Read MoreThe Role of Calcium Hydroxylapatite (Radiesse) in Nonsurgical Aesthetic Rejuvenation
Radiesse® (Bioform Medical, San Mateo, CA) is a synthetic calcium hydroxylapatite microsphere filler suspended in an aqueous carrier gel. Radiesse currently has indications in the United States (U...
Read MoreConsiderations for the Use of Injectable Poly-L-lactic Acid in People of Color
With demand for minimally invasive cosmetic procedures rising in patients of color, it is becoming increasingly important for clinical dermatologists to be aware of specific needs of these patients. ...
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Making the Right Choices: Attaining Predictable Aesthetic Results WithDermal Fillers
The types and number of dermal fillers have evolved, allowing clinicians to select the most appropriate agent for each specific use. Filler properties differ both between and among classes, so clinic...
Read MorePipeline Previews
Face and Neck Revitalization With Platelet-rich Plasma (PRP): Clinical Outcome ina Series of 23 Consecutively Treated Patients
Background: Platelet-rich plasma (PRP) has long been known as an effective treatment in various surgical and medical fields. Face and neck revitalization with PRP is an application that is currently ...
Read MoreResident Rounds
Nanoparticles: A Closer Look at Their Dermal Effects
Nano-sized particles represent a unique class of materials with novel physiochemical properties due to increased surface area. Many sunscreens and cosmetics are now using nano-sized titanium dioxide ...
Read MoreClinical Trial Review
Benzoyl Peroxide Development, Pharmacology, Formulation and Clinical Uses in Topical Fixed-combinations
Benzoyl peroxide (BPO) is a commonly used and highly effective topical treatment for acne that is available in concentrations from 2.5–10%. The compound is not associated with bacterial resist...
Read MoreAn Approach to Pruritus in Atopic Dermatitis: A Critical Systematic Review of theTacrolimus Ointment Literature
Persistent pruritus, or itch, is one of the earliest symptoms of atopic dermatitis (AD). When pruritus is untreated, the incessant scratching response by the patient can increase the inflammatory res...
Read MoreSecond-generation Antihistamines for theTreatment of Chronic Idiopathic Urticaria
Chronic idiopathic urticaria (CIU) is a serious disorder that can greatly compromise quality of life. While H1 antihistamines are the accepted first-line treatment for CIU, older generations of these...
Read MoreA Comparative Study Evaluating the Tolerability and Efficacy of Two TopicalTherapies for the Treatment of Keloids and Hypertrophic Scars
Background: Onion extract gel (OE) and 0.5% hydrocortisone, silicone and vitamin E lotion (HSE) are two over-the-counter preparations used to enhance the cosmesis of keloids and hypertrophic scars. ...
Read MoreTrends in the Treatment of Acne Vulgaris: Are Measures Being Taken to Avoid Antimicrobial Resistance?
Background: Acne vulgaris has been treated with long-term courses of antibiotics since the 1960s. Antibiotic-resistance of Propionibacterium acnes (P. acnes) was first documented in the late 1970s, a...
Read MoreAntifungal Activity, Experimental Infections and Nail Permeation of an InnovativeCiclopirox Nail Lacquer Based on a Water-soluble Biopolymer
P-3051 is an innovative 8% ciclopirox nail lacquer, based on hydroxypropyl chitosan (HPCH) as a film-forming agent. The authors’ aim was to investigate P-3051’s in vitro antifungal acti...
Read MoreIs Topical Dapsone Safe in Glucose-6-phosphate Dehydrogenase-deficient andSulfonamide-allergic Patients?
Topical dapsone gel 5% is indicated for the treatment of acne vulgaris and has been marketed since late 2008. The topical formulation retains the anti-inflammatory benefits of dapsone while minimizin...
Read MoreAlopecia: Botanical Approaches in Review
The use of herbal medications in dermatologic disease has become common practice among consumers. In this paper, the authors review and discuss the existing evidence-based botanical modalities in the...
Read MoreUse of a Collagen-glycosaminoglycan Copolymer (Integra) in Combination WithAdjuvant Treatments for Reconstruction of Severe Chest Keloids
Background: Keloids occurring on the chest can be deforming with significant painful sequelae for patients. These lesions can pose a therapeutic dilemma for the dermatologic surgeon as certain excisi...
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Case Reports
X-linked Chronic Granulomatous Disease With Voriconazole-inducedPhotosensitivity/Photoaging Reaction
Due to the mutations in the nicotinamide dinucleotide phosphate (NADPH) oxidase complex in X-linked chronic granulomatous disease (CGD), the phagocytic activity in these patients is curtailed by a dy...
Read MoreA Case of Erythromelalgia: Good Response to Treatment With Gabapentin
Erythromelalgia is a rare chronic disorder characterized by intense burning pain, redness, swelling and increased skin temperature. It occurs primarily in the feet, but may also involve the hands, fa...
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