Issue Archive
February 2010 | Volume 9 | Issue 2
Original Articles
Clinical Trial Review
A Randomized, Investigator-Blinded Trial to Assess the Antimicrobial Efficacy of aBenzoyl Peroxide 5%/Clindamycin Phosphate 1% Gel Compared With a Clindamycin Phosphate 1.2%/Tretinoin 0.025% Gel in the Topical Treatment of Acne Vulgaris
Background: Combination products in which the individual components have different mechanisms of antimicrobial action have been shown in many disease states to provide the most effective therapy.
Read More Population Education in Preventing Skin Cancer: From Childhood to Adulthood
Skin cancer is the most commonly diagnosed cancer in populations of predominantly Caucasian origins. As the main cause of skin cancer is excessive sun exposure among a sun-sensitive population, most ...
Read MoreManagement of Merkel Cell Carcinoma With Emphasis on Small Primary Tumors — A Case Series and Review of the Current Literature
A case series of Merkel cell carcinoma (MCC) is reported here and illustrates some of the current controversies in clinical management of this disease. From 1988–2007, 145 cases (74 men and 71...
Read MoreKeratoacanthomas: Overview and Comparison Between Houston and Minneapolis Experiences
Keratoacanthomas represent approximately 1% of skin malignancies treated in a Mohs practice in Houston, TX. The authors compared the age of onset, sex, location and month of prevalence of keratoacant...
Read MoreThe Efficacy of Photodynamic Therapy in Treatment of Recurrent Squamous Cell and Basal Cell Carcinoma
Objectives: A number of investigations have already been carried out to assess the effect of photodynamic therapy (PDT) on primary basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) lesions...
Read MoreDermoscopy and Its Impact on Skin Cancer Diagnostics
Dermoscopy has clearly had a profound impact on the clinical diagnosis of pigmented lesions. It has been shown not only to be useful in the early diagnosis of melanomas but also, more recently, for t...
Read MoreComparative Efficacy and Safety Results of Topical Hemostatic Powder and Sterile Compressed Foam Sponge in Second Intention Healing Following MohsMicrographic Surgery
This study compared the safety and efficacy of a non-prescription topical hemostatic powder (THP) containing a hydrophilic polymer and a potassium-based salt (group 1) to a sterile, compressed surgic...
Read MoreNews, Views and Reviews
Pipeline Previews
Case Reports
Sorafenib-Induced Psoriasiform Eruption in a Patient With Metastatic Thyroid Carcinoma
Sorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis and is used for the treatment of advanced renal cell carcinoma, unresectable hepatocellular carcinoma, and o...
Read MoreTreatment of Burn Scar Using a Carbon Dioxide Fractional Laser
In Asian patients, ablative laser therapies are seldom used to treat burn scars due to posttreatment dyschromia, especially when nonfacial areas are treated. The non-ablative 1550-nm erbium-doped fra...
Read MoreA Patient With Neviod Basal Cell Carcinoma Syndrome Treated Successfully With Photodynamic Therapy: Case Report and Review of the Literature
Nevoid basal cell carcinoma syndrome (NBCCS) is a genetic disorder characterized by multiple basal cell carcinomas (BCCs) in addition to skeletal abnormalities and other neoplasms. Difficulty lies in...
Read MoreCharcot-Marie-Tooth Disease and Multiple Malignant Melanomas: A Case Report
The incidence of malignant melanoma has reached more than 62,000 people this past year alone. Much is unknown about the genetic predisposition of this cancer. The authors present a 62-year-old woman ...
Read MoreOsteoinvasive Subungual Melanoma: A Case and Review
Subungual melanoma is a relatively rare variant of melanoma, accounting for 0.7–3.5% of all melanoma cases in the Caucasian population. Curiously, it occurs in 8–33% of cases in black, ...
Read MoreA Case of Multiple Skin Cancers in a Patient on Combination ImmunosuppressiveTherapy For Behcet’s Disease
Skin cancer risk from the use of immunosuppressive medications used to treat inflammatory conditions is not well understood, though studies clearly establish an exaggerated risk of skin cancer in sol...
Read MoreUtilization of a New Tissue Expander in the Closure of a Large Mohs Surgical Defect
Background: Malignant proliferating trichilemmal tumor (MPTT) is a rare neoplasm originating in the outer sheath of a hair follicle that often presents as a slowly enlarging, painful, subcutaneous sc...
Read MoreRapid Wound Re-epithelialization and Basal Cell Carcinoma Clearance After MohsMicrographic Surgery With Postoperative Photodynamic Therapy
Background: Methyl aminolevulinic acid photodynamic therapy (MAL-PDT) has antitumor activity and may promote wound healing. Superficial and nodular basal cell carcinomas (BCCs) have been successfully...
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