Issue Archive
February 2021 | Volume 20 | Issue 2
Original Articles
The Impact of the COVID-19 Pandemic on Physician-Pharmaceutical Office-Based Interactions
Background: COVID-19 has had significant negative economic ramifications on dermatologic care delivery, including curtailing live on-site physician-pharmaceutical-representative interactions (PPRI). <...
Read MoreIntralesional 5-Fluorouracil for Treatment of Non-Melanoma Skin Cancer: A Systematic Review
Background: Surgical excision is the paradigm treatment option for non-melanoma skin cancer (NMSC), however intralesional fluorouracil (IL 5-FU) is an efficacious alternative and superior to other che...
Read MoreInflammaging in Dermatology: A New Frontier for Research
As humans age, our ability to manage certain types of inflammation is reduced. As a result, we experience chronic, low-grade inflammation, which has been termed “inflammaging”. This type o...
Read MoreDermatologists’ Perspectives on Defining Moderate Psoriasis: The Canadian Moderate Psoriasis Survey
Background: Psoriasis is commonly classified as either mild or moderate to severe, without specific parameters to differentiate moderate versus severe disease. This may lead to patients with moderate ...
Read MoreDo Antimicrobial Resistance Patterns Matter? An Algorithm for the Treatment of Patients With Impetigo
Background: Impetigo, a highly contagious bacterial skin infection commonly occurring in young children, but adults may also be affected. The superficial skin infection is mainly caused by Staphylococ...
Read MoreHospitalization in Patients with Psoriasis: Impact of Biological Therapies on Temporal Evolution
Background: Psoriasis is an immunomediated disease mostly controlled at the outpatient level, although there is a low percentage of patients that require systemic drugs or even hospitalization for an ...
Read MoreIngenol Mebutate as Treatment of Squamous Cell Carcinoma In Situ: A Case Series
Ingenol mebutate (IM) is a novel drug currently only FDA-approved for the treatment of actinic keratosis. However, it has been extensively used off-label to treat multiple other skin disorders. In rec...
Read MorePatient Perceptions and Satisfaction With Teledermatology During the COVID-19 Pandemic: A Survey-Based Study
Background: The COVID-19 pandemic has drastically changed the practice of dermatology as social distancing guidelines have led to a shift from in-office care to virtual telehealth (teledermatology). W...
Read MoreNew Protocol for Long-Term Results With a Multi-Pulse Nd:YAG Laser for Melasma Treatment: A Descriptive Cohort Study
Background: Melasma is a photoaging condition with a typical clinical and histological pattern under a genetic and epigenetic context. Over the years, many treatments modalities have been proposed inc...
Read MoreDifferences in Depression and Distress Between Acne Patients on Isotretinoin vs Oral Antibiotics
Background: Little is known regarding differential effects of systemic anti-acne treatments on mental health.
Objective: To determine whether differences exist in mental health outcomes between ...
Read MoreEfficacy and Tolerability of a Novel Topical Treatment for Neck: A Randomized, Double-blind, Regimen-Controlled Study
The neck plays a telling role as an age indicator. Due to its anatomy and function, neck skin ages differently than facial skin and special considerations need to be taken when providing treatment. A ...
Read MoreA Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma
Basal cell carcinoma (BCC) is the most common malignancy in fair-skinned populations. Most cases are successfully treated with surgery, but in advanced BCC—including locally advanced BCC and met...
Read More
Features
Vitamin K2 Awareness in Sun-Protected Patients Supplementing With Vitamin D
Dermatologists often recommend vitamin D for sun-protected patients. Most patients are not aware of the key role vitamin K2 plays in vitamin D metabolism and do not receive sufficient dietary vitamin ...
Read MoreA Retrospective Chart Review of Inflamed Epidermal Inclusion Cysts
Background: Epidermal inclusion cysts (EIC) are one of the most common forms of cysts found on and/or underneath the skin. Inflamed EICs typically show signs and symptoms such as pain and erythema, mi...
Read MoreResponse to “Assessing a Paradigm Shift: Perceptions of the USMLE Step 1 Scoring Change to Pass/Failâ€
We commend Wei et al1 for highlighting the fundamental shift that dermatology program directors (PDs) and students alike will experience following the change of the USMLE Step 1 to pass/fail....
Read MoreAcitretin for Secondary Prevention of Keratinocyte Cancers in a Veteran Population: A Retrospective Cohort Study
Acitretin, a vitamin A derivative used for psoriasis, can prevent keratinocyte carcinoma (KC). It induced regression of keratoacanthomas (KA) in animal models, presumably by activating retinoic acid a...
Read More
Case Reports
Intense Pulsed Light: A Methodical Approach to Understanding Clinical Endpoints
Background: Intense Pulsed Light (IPL) is a non-coherent polychromatic broadband filtered flashlamp that emits light in the spectrum of approximately 400–1200 nm. Its effects on photorejuvenatio...
Read More
