Issue Archive
February 2006 | Volume 5 | Issue 2
Editorials
Photodynamic Therapy: Current and Emerging Applications
This supplement to the Journal of Drugs in Dermatology was supported by Dusa Pharmacueticals....
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Original Articles
Safety Update on Commonly Used Psychotropic Medications in Dermatology
It is the experience of dermatologists worldwide that a significant proportion of their patient population has underlying psychological components to their dermatologic complaints. Since these patien...
Read MorePart 1 of a 2 Part Article: A Comprehensive Review of Imatinib Mesylate (Gleevec) for Dermatological Diseases
Imatinib mesylate (Gleevec, also known as STI-571), is an approved oral treatment for patients with chronic myeloid leukemia (CML). It blocks the activity of Abelson cytoplasmic tyrosine kinase (ABL)...
Read MoreThe Position not the Presence of the Halogen in Corticosteroids Influences Potency and Side Effect
Many topical corticosteroids currently on the market contain a halogen substitution at the C6, C9, or the side-chain C21 position of the corticosteroid skeleton. These modifications have enhanced the...
Read MoreOne-Week Treatment with 0.5% Fluorouracil Cream Prior to Cryosurgery in Patients with Actinic Keratoses: A Double-Blind, Vehicle-Controlled, Long-Term Study
Topical fluorouracil is currently approved for the treatment of actinic keratosis (AK) and is often used prior to or following cryosurgery as interval therapy in patients with severe AK lesions. No r...
Read MoreThe Use of Photodynamic Therapy in Dermatology: Results of a Consensus Conference
Photodynamic therapy (PDT) has significant promise in improving outcomes of patients with a variety of cutaneous conditions. A group of experts met to review the principles, indications, and clinical...
Read MoreBilateral Comparison of the Efficacy and Tolerability of 3% Diclofenac Sodium Gel and 5% 5-Fluorouracil Cream in the Treatment of Actinic Keratoses of the Face and Scalp
Actinic keratoses (AKs) are a common precancerous condition and are said to account for 14% of visits to dermatologists in the US each year. Along with cryotherapy, topical treatments are a mainstay ...
Read MoreThe Clinical Impact of Vehicle Technology Using a Patented Formulation of Benzoyl Peroxide 5%/Clindamycin 1% Gel Containing Dimethicone and Glycerin in Combination with Topical Retinoids and Sunscreens
A major challenge encountered in clinical practice in patients with acne vulgaris is irritation related to topical medications used for treatment. Advances in vehicle technology have improved formula...
Read MoreMechanisms of Action of New Treatment Modalities for Actinic Keratosis
Actinic keratosis (AK) constitutes the initial lesion in a disease continuum that can progress to invasive squamous cell carcinoma (SCC). In this article, we describe the mechanisms of action, tolera...
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Features
Case Reports
Poikilodermatous Variant of Mycosis Fungoides
Mycosis Fungoides (MF) is a T-cell lymphoma initially presenting in the skin. Many clinical variants exist including follicular, vesicular, poikilodermic, hypo- and hyperpigmented, ichthyosiform and ...
Read MoreIndoor Tanning—Magnitude of the Health Issue
An Unusual Presentation of Refractory Cutaneous Langerhans Cell Histiocytosis in an Adult
Primary cutaneous adult-onset Langerhans cell histiocytosis is a rare disorder typically characterized by a diffuse papular rash accentuated in a seborrheic distribution. We present a unique case of ...
Read MoreInfliximab Associated New-Onset Psoriasis
Infliximab infusion is not yet FDA-approved for psoriasis but has been reported to be very effective for plaque psoriasis. We report 2 patients without a history of psoriasis who after administration...
Read MoreRapid Growth of Merkel Cell Carcinoma after Treatment with Rituximab
Merkel cell carcinoma is an uncommon neuroendocrine carcinoma of the skin. We report a case of rapid growth of Merkel cell carcinoma after treatment with rituximab, a new anti-CD20 monoclonal antibod...
Read MoreThe Incidence of Recurrent Herpes Simplex and Herpes Zoster Infection during Treatment with Arsenic Trioxide
We report the incidence of varicella zoster virus (VZV) and herpes simplex virus (HSV) infection in patients with multiple myeloma and colon cancer who were treated with arsenic trioxide for their di...
Read MoreParaffinomas of the Facial Area: Treatment with Systemic and Intralesional Steroids
We present a case of a 32-year-old male patient with a history HIV infection, who administered vitamin E and almond oil into the malar region and chin. On histology the main pathological finding was ...
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