Issue Archive
September 2005 | Volume 4 | Issue 5
Original Articles
Biologic Therapy for Psoriasis: An Update on the Tumor Necrosis Factor Inhibitors Infliximab, Etanercept, and Adalimumab, and the T-Cell-Targeted Therapies Efalizumab and Alefacept
Psoriasis is a chronic skin disorder that affects approximately 2% of the US and European population. Over the last several years, one of the major focuses in psoriasis research has been the developm...
Read MoreAssessment of Skin Barrier Function in Rosacea Patients with a Novel 1% Metronidazole Gel
The skin of patients with rosacea is extremely sensitive and hyper-reactive to dietary, environmental, and topical factors. Accordingly, the management of rosacea involves not only choosing appropria...
Read MoreInpatient Management of Severe Psoriasis
Historically, severe psoriasis frequently required inpatient hospitalization for several weeks to reduce symptoms and prevent morbidity and mortality. Despite declining hospitalization rates there re...
Read MoreThe Role of Number of Treatments in Laser-Assisted Hair Removal Using a 755-nm Alexandrite Laser
Background: It is generally accepted that multiple laser treatments yield more effective clinical results; however, it is not clearly known whether increasing the number of treatments would affect th...
Read MoreEvaluation of a Flexible New Liquid Polymer Wound Dressing
Occlusive dressings are the foundation of wound care and have been shown to speed epithelialization and healing of surgical sites. Many different dressings have been introduced over the years includi...
Read MoreThe Face and Mind Evaluation Study: An Examination of the Efficacy of Rosacea Treatment Using Physician Ratings and Patients’ Self-Reported Quality of Life
Objective: To examine both the short-term clinical efficacy and quality-of-life changes resulting from treatment of rosacea with regimens that reflect the participating physicians’ standards o...
Read MoreA Large 12-Month Extension Study of an 8-Week Trial to Evaluate the Safety and Efficacy of Triple Combination (TC) Cream in Melasma Patients Previously Treated with TC Cream or One of its Dyads
This was a 12-month extension of a randomized, investigator-blinded, multicenter, 8-week trial with triple combination (TC) cream in facial melasma. A total of 585 patients were enrolled in the study...
Read MoreImiquimod and Superficial Skin Cancers
Topical imiquimod has opened an entirely new area of dermatology that previously did not exist: medical therapy for skin cancers. While surgery will continue to play a vital role in treating more agg...
Read MoreComparison of Clindamycin/Benzoyl Peroxide, Tretinoin Plus Clindamycin, and the Combination of Clindamycin/Benzoyl Peroxide and Tretinoin Plus Clindamycin in the Treatment of Acne Vulgaris: A Randomized, Blinded Study
In the treatment of mild to moderate acne vulgaris, the combination of an antibiotic and benzoyl peroxide provides enhanced efficacy over the individual agents, with the potential to decrease the eme...
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Features
Case Reports
Reticulate Hyperpigmentation Secondary to 5-Fluorouracil and Idarubicin
Although cutaneous reactions from antineoplastic therapy are common, a reticulate pattern of hyperpigmentation has not been frequently reported in the literature. We report 2 cases of reticulate hype...
Read MoreSuccessful Treatment of Mycobacterium Marinum Infection with Minocycline after Complication of Disease by Delayed Diagnosis and Systemic Steroids
Mycobacterium marinum, an aerobic, non-tuberculous, environmental mycobacterium, is the etiologic agent responsible for “fish tank granuloma.â€1 Found in aquatic environments, particularly...
Read MorePunctate Palmoplantar Keratoderma (Buschke-Fischer-Brauer Disease) with Psoriasis: A Rare Association Showing Excellent Response to Acitretin
Hereditary punctate palmoplantar keratoderma (Buschke-Fischer-Brauer disease) is a rare disorder of keratinization. We describe here a 49-year-old male patient of this condition with many unusual fea...
Read MoreEffective Treatment of Female Androgenic Alopecia with Dutasteride
Dihydrotestosterone is the main molecule responsible for androgenic alopecia. Finasteride, which reduces transformation of testosterone into dihydrotestosterone and decreases dihydrotestosterone acti...
Read MoreCutaneous Leiomyomatosis and Parotid Pleomorphic Adenoma
We present a case of cutaneous leiomyomas (CL) arising in a pleomorphic adenoma (PA) of the parotid gland. PA and CL are benign tumors arising from the parotid gland and the erector pilli muscle, res...
Read MorePancytopenia after a Single Intradermal Infiltration of Methotrexate
Methotrexate-related hematologic toxicity may include leukopenia, thrombocytopenia, megaloblastic anemia, and pancytopenia. We report a woman with hypertensive renal disease who was receiving hemodia...
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