Issue Archive
April 2019 | Volume 18 | Issue 4
Editorials
Matrix Revisited: Innovative Approach for Tretinoin
The history of tretinoin and its use in dermatology is a testament both to the drug’s well-established efficacy and its potential to cause skin irritation. Over more than four decades, the drug ...
Read MorePractical Applications for Medical and Aesthetic Treatment of Skin of Color With a New 650-Microsecond Laser
Individuals with skin of color are a rapidly growing portion of the cosmetic procedures market. There are unique challenges to treating skin conditions in skin of color patients. This article and roun...
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Original Articles
Observational Study of Clindamycin Phosphate and Tretinoin Gel for the Treatment of Acne
INTRODUCTION: Acne vulgaris can cause pain/discomfort and have a negative impact on quality of life (QOL). Clin-RA is an acne treatment consisting of clindamycin phosphate 1.2% and tretinoin 0.025%, w...
Read MoreUse of Apremilast in Patients Who Are Dissatisfied With Stable Maintenance Topical Therapy
OBJECTIVE: To explore the impact of adding apremilast to a regimen of topical corticosteroids in patients with moderate plaque-type psoriasis. RESEARCH DESIGN AND METHODS: This was an open label, 16...
Read MoreA Double-Blind Randomized Controlled Trial Evaluating the Efficacy and Tolerability of a Topical Body Treatment in Combination With Cryolipolysis Procedures
Background: Non-surgical fat reduction through cold application, cryolipolysis, is an extremely popular procedure. Apoptosis of the fat cell content may take around 3 months to resolve. Objective:...
Read MoreA Randomized Controlled Tolerability Study to Evaluate Reformulated Benzoyl Peroxide Face Washes for Acne Vulgaris
Introduction: This randomized, evaluator-blind, single-center, parallel-group study sought to evaluate the tolerability of two reformulated face washes containing benzoyl peroxide (BPO) in adults wit...
Read MoreThe Effect of Calcipotriene-Betamethasone Dipropionate Aerosol Foam versus Vehicle on Target Lesions in Moderate Severity Plaque Psoriasis: Focus on Elbows and Knees
Calcipotriene 0.005%, a vitamin D analog, plus betamethasone dipropionate 0.064%, a high potency topical corticosteroid, are combined in an aerosol foam formulation proven to be effective and safe us...
Read MoreRed Deer Umbilical Cord Lining Mesenchymal Stem Cell Extract Cream for Rejuvenation of the Face
BACKGROUND: Aging is a multifactorial process that involves all components of the skin. Both intrinsic and extrinsic forces play a role in this aging process. A new patented protein mix derived from ...
Read MoreAn Open Label Study of an Occlusive Heat Patch in the Treatment of Warts
BACKGROUND: Local hyperthermia has been demonstrated to be a safe and efficacious treatment for warts. OBJECTIVE: We aimed to evaluate the safety and efficacy of an epicutaneous heat patch to induc...
Read MoreNon-Surgical Fat Reduction and Topical Modulation of Adipose Tissue Physiology
Non-surgical fat reduction procedures have gained in popularity over the past few years and remain in great demand. The process results in accumulation of breakdown products, lipid droplets, that are...
Read MoreConcerns and Treatment Satisfaction in Patients Being Treated With Azelaic Acid Foam for Rosacea
Objective: To describe patient characteristics, concerns, side effects, treatment satisfaction, and quality of life (QoL) of rosacea patients currently being treated with monotherapy azelaic acid foa...
Read MoreTreatment of Psoriasis With Biologics and Apremilast in Patients With a History of Malignancy: A Retrospective Chart Review
INTRODUCTION: Biologics have transformed the management of moderate-to-severe psoriasis. The risk of developing a malignancy during treatment is an important consideration, and many studies have been...
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Case Reports
Grover’s Disease Treated With Total Skin Electron Beam Radiotherapy
Persistent Grover's disease can cause significant symptoms of pruritus thereby decreasing quality of life. Many patients undergo successful conservative management of their disease; however, a subset...
Read MoreSuccessful Treatment of Refractory Plaque-Type Psoriasis and Psoriatic Arthritis With Guselkumab and Adalimumab Combination Therapy: A Case Report
COPY: A number of biologics have been approved for use in plaque-type psoriasis. They act by either blocking the action of a specific type of cell or protein in the immune system. CASE PRESENTATIO...
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Supplements
Practical Applications for Medical and Aesthetic Treatment of Skin of Color With a New 650-Microsecond Laser
The following roundtable is edited from discussion between the authors concerning treatment with the 650-microsecond 1064nm Nd:YAG laser. These dermatologist experts share their expertise, experience,...
Read MoreTretinoin Formulation: From Microsponges to Polymeric Emulsion
The history of tretinoin and its use in dermatology is a testament both to the drug’s well-established efficacy and its potential to cause skin irritation. Over more than four decades, the drug ...
Read MorePolymeric Emulsion Technology Applied to Tretinoin
The Microsponge Delivery System (MDS) for Tretinoin: A First Attempt at Reducing Irritation The Microsponge Delivery System (MDS) is a controlled drug delivery system that encapsulates the active drug...
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