Issue Archive
November 2017 | Volume 16 | Issue 11
Editorials
New Insight Into the Multifactorial Pathophysiology of Hair Loss: Inflammation, Stress, and Follicle Biology Take Front Stage
As our understanding of the microenvironment of the hair follicle deepens, it is becoming increasingly clear that targeting a single pathway in this complex system is not ideal. Androgens, cortisol, a...
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Original Articles
Managing Seborrheic Keratoses: Evolving Strategies for Optimizing Patient Outcomes
The seborrheic keratosis is the most common benign skin tumor of middle-aged and elderly adults, affecting nearly 83 million individuals in the US alone. Although these are benign lesions, many patien...
Read MoreTreatment of Photoaging With a Dual-Wavelength, 532 nm and 1,064 nm Picosecond-Domain Laser Producing a Fractionated Treatment Beam Using a Holographic Optic
BACKGROUND: A dual-wavelength, picosecond-domain, fractionated laser delivering 1,064nm and 532nm laser energy through a holographic optic was investigated for safety and effectiveness at improving th...
Read MoreIn-Vivo Histological Analysis of a Fractional CO2 Laser System Intended for Treatment of Soft Tissue
BACKGROUND: Fractional ablative lasers have been shown to be safe and effective for improving wrinkles, scars, skin texture, and dyspigmentation. However, the exact effects of this technology in vivo ...
Read MoreLasers, Light, and the Treatment of Acne: A Comprehensive Review of the Literature
Introduction: Acne vulgaris is common dermatologic condition with an estimated prevalence of 70 to 87%. Acne has been shown to have a significant impact on patient quality of life and mental health, e...
Read MoreDisparity in Cutaneous Pigmentary Response to LED vs Halogen Incandescent Visible Light: Results from a Single Center, Investigational Clinical Trial Determining a Minimal Pigmentary Visible Light Dose
Background: While most of the attention regarding skin pigmentation has focused on the effects of ultraviolet radiation, the cutaneous effects of visible light (400 to 700nm) are rarely reported. Obj...
Read MoreA Retrospective Study on Efficacy of Pulsed Dye Laser and Intense Pulsed Light for the Treatment of Facial Telangiectasia
Both pulsed dye laser (PDL) and intense pulsed light (IPL) systems have been demonstrated to be effective for treatment of facial telangiectasia, however there have been very few comparative studies b...
Read MoreEfficacy of Low-Fluence Nd:YAG 1064 nm Laser for the Treatment of Post-Inflammatory Hyperpigmentation in the Axillary Area
OBJECTIVE: Post-inflammatory hyperpigmentation results in aesthetically unpleasant discoloration of the skin in the affected area. The efficacy of low-fluence Q-switched 1064-nm Nd:YAG laser has so fa...
Read MoreA Randomized, Investigator-Blinded Comparison of Two Topical Regimens in Fitzpatrick Skin Types III-VI With Moderate to Severe Facial Hyperpigmentation
Purpose: Though hydroquinone (HQ) remains the gold standard for treatment of hyperpigmentation, concerns about its safety have prompted the development of HQ-free topical skin lightening systems. Obj...
Read MoreManagement of Severe Acne Vulgaris With Topical Therapy
Acne vulgaris (acne) is the most common skin disease we see in dermatology practice. Although rare in childhood, severe acne can affect up to 12% of the adolescent population. A chronic disease, it re...
Read MoreNovel Treatment Using Low-Dose Naltrexone for Lichen Planopilaris
Lichen planopilaris (LPP) is a variant of lichen planus that affects the scalp causing scarring hair loss. Patients also frequently experience symptoms of scalp itch, pain, and burning. To date, there...
Read MorePort-Wine Stains: A Focused Review on Their Management
Port-wine stain (PWS) is the second most common congenital vascular malformation characterized as ectatic capillaries and venules in the dermis that clinically appears as a deep red to purple patch on...
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Features
2017 ODAC CONFERENCE ARTE POSTER WINNER: Bioinformatics Analysis of the Inflammatory Acne Transcriptome Supports Mechanisms of Action for Current Treatments and Predicts Novel Therapies In Vivo
Acne vulgaris, a common disorder of pilosebaceous follicles, adversely affects quality of life in patients. Formation of papules and pustules in inflammatory acne is orchestrated by a sustained host i...
Read MoreNEWS, VIEWS, & REVIEWS: Memory Age: What It Is, Why It’s Important, and Practical Applications for Medical Aesthetics Practitioners
A recent study by a leading medical aesthetics practice has revealed that women have a “Memory Age†that is about 10 years younger than their actual age. Skin by Lovely (Portland, OR; Sant...
Read MoreThe Alexiades Filler Lift Method
Senior Resident Peer-to-Peer Case Studies
The content of these case studies, ideal to review during peer study groups, was developed by Julia Schwartz, MD and Thomas Lee, MD under the guidance of dermatologist Adam Friedman, MD, FAAD, Associa...
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Case Reports
An Elusive Amelanotic Melanoma and Review of Dermoscopic Findings
Amelanotic melanoma (AM) is one of the great masqueraders in dermatology. It is a very difficult clinical diagnosis to make because these tumors are devoid of pigment and other clues of melanoma. They...
Read MoreUse of Isoquercetin in the Treatment of Prurigo Nodularis
Atopic dermatitis and prurigo nodularis result from complex interactions between the skin, the immune system, and the external environment. The pruritus associated with these conditions greatly impact...
Read MoreVancomycin Infiltrate-Induced Dermatitis Mimicking Bullous Cellulitis
Extravasation of medications can manifest as tenderness, pain, tissue necrosis, and thrombophlebitis and lead to infection and severe long-term complications. Risk factors for leakage of medications i...
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Supplements
A New Look at Pathogenesis of Hair Loss
While there are a number of products that can help healthy hair look healthier, shampoos or vitamins alone can’t truly regrow thinning hair. As dermatology providers, we realize this not only be...
Read MoreNew Insight Into the Pathophysiology of Hair Loss Trigger a Paradigm Shift in the Treatment Approach
Hair loss affects millions of men and women of all ages and ethnicities, impacting appearance, social interactions, and psycho-emotional well-being. Although a number of options are available, they ar...
Read MoreA Novel Multi-Targeting Approach to Treating Hair Loss, Using Standardized Nutraceuticals
Hair loss is a complicated problem that causes significant concern for those who are affected. Patients seeking medical treatment have limited options that include topical minoxidil and oral finasteri...
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