Issue Archive
June 2015 | Volume 14 | Issue 6
Original Articles
Validation of a New Patient-Reported Outcome Measure for Facial Acne: The Acne Symptom and Impact Scale (ASIS)
OBJECTIVE: The objective of this study was to evaluate the psychometric performance of the Acne Symptom and Impact Scale (ASIS) for use in adolescents and adults with acne vulgaris.
METHODS: Psyc...
Read MoreAn Open Label, Phase 2 Study of MABp1 Monotherapy for the Treatment of Acne Vulgaris and Psychiatric Comorbidity
BACKGROUND: Acne vulgaris is a common inflammatory skin disorder. There remain few rapid, safe, and effective therapy options for patients with moderate to severe acne vulgaris that also address psych...
Read MoreTopical Treatments in Acne Vulgaris: Guidance for the Busy Dermatologist
Acne is a very common skin disease; frequently seen in adolescents and often persisting or occurring into adulthood. Topical therapy is very effective in mild to moderate disease, and is used as maint...
Read MoreAntimicrobial Activity of Pomegranate and Green Tea Extract on Propionibacterium Acnes, Propionibacterium Granulosum, Staphylococcus Aureus and Staphylococcus Epidermidis
We used pomegranate extract (POMx), pomegranate juice (POM juice) and green tea extract (GT) to establish in vitro activities against bacteria implicated in the pathogenesis of acne. Minimum inhibitor...
Read MoreEfficacy and Safety of Subantimicrobial Dose, Modified-Release Doxycycline 40 mg Versus Doxycycline 100 mg Versus Placebo for the treatment of Inflammatory Lesions in Moderate and Severe Acne: A Randomized, Double-Blinded, Controlled Study
INTRODUCTION: Routine use of doxycycline (DC) 100 mg for the treatment of moderate to severe acne may be associated with gastrointestinal adverse events (AEs), thus potentially impacting patient adher...
Read MorePilot Study of Topical Copper Chlorophyllin Complex in Subjects With Facial Acne and Large Pores
BACKGROUND: Acne vulgaris is one of the most common skin diseases treated by dermatologists. Salts of copper chlorophyllin complex are semi-synthetic naturally-derived compounds with antioxidant, anti...
Read MoreEvaluation of Seasonal Changes in Facial Skin With and Without Acne
The objective of this study was to compare facial skin of adolescent males with (acne) and without acne (non-acne) over the course of 1 year. At study entry, presence of acne was determined by clinica...
Read MoreDapsone Gel in the Treatment of Papulopustular Rosacea: A Double-Blind Randomized Clinical Trial
BACKGROUND: We aimed to evaluate the effects of 5% dapsone gel compared with 0.75% metronidazole gel in the treatment of papulopustular rosacea.
METHODS: In a double-blind randomized clinical tri...
Read MoreIn Vitro Nail Penetration and Antifungal Activity of Tavaborole, a Boron-Based Pharmaceutical
An effective topical antifungal medication must penetrate through the nail plate at sufficient concentrations to eradicate the fungal infection. Tavaborole topical solution, 5% is a novel boron-based ...
Read MoreTopical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study
BACKGROUND: Alopecia areata (AA) is considered a T-cell mediated autoimmune disease characterized by patchy loss of hair from scalp and other body parts with no definitive treatment. Calcipotriol is a...
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Features
Resident Rounds: Part I - Program Spotlight: The University of Miami/Jackson Memorial Hospital Dermatology Residency Program
Resident Rounds is a section of the JDD dedicated to highlighting various dermatology departments with residency training programs. Resident Rounds includes 3 sections: (1) a program spotlight highlig...
Read MoreManagement of Acne & Rosacea: Working Toward the Same Goals…Facing New Challenges
What Does the Data from the ATX-101 Phase I Safety and Pharmacokinetic Study Tell Us?
Board Review - In Partnership with Derm In-Review
The content of these questions and answers are taken from Derm In-Review. For more practice Q&A and Board prep study tools, visit DermInReview.com/Merz....
Read MoreTreatment of Rosacea: Expert Insight on Trends and Best Practice
Resident Rounds: Part II - Hereditary Syndromes Associated With Increased Risk of Keratinocyte Carcinomas
Academia and the Millennials: Trending Career Choices of Graduating Dermatology Residents 1999-2012
Resident Rounds: Part III - Case Report: A Non-Syndromic Case of Multiple Unilateral Nodular and Pigmented Basal Cell Carcinomas
Although basal cell carcinomas (BCC) are relatively common, particularly in older individuals, the development of multiple BCCs at a young age can indicate an associated genetic disorder. Several case...
Read MoreClinical Trial Report
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MorePipeline Previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
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Case Reports
Human Adipocyte Apoptosis Immediately Following High Frequency Focused Field Radio Frequency: Case Study
BACKGROUND: A previously published study used a radio frequency (RF) focused field device (Vanquish, BTL Industries Ltd., Framingham, MA) to reduce porcine abdominal fat. The purpose of this case stud...
Read MoreSevere Tacrolimus-Induced Granulomatous Rosacea Recalcitrant to Oral Tetracyclines
Topical tacrolimus has been observed to induce granulomatous rosacea (GR) in prior case reports and series. In most cases, patients recover fully after withdrawing tacrolimus and initiating doxycyclin...
Read MoreSuccessful Treatment of a Lichenoid-Like Granulomatous Reaction to Purple Tattoo Pigment With Intralesional Kenalog
Tattoo reactions can be clinically challenging to diagnose and treat. We present a case of a biopsy-proven granulomatous reaction to purple tattoo ink that clinically mimicked lichen planus. This reac...
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