Issue Archive
May 2015 | Volume 14 | Issue 5
Original Articles
Five-Year Trend in the Number of Dermatologic Clinical Drug Trials Registered on ClinicalTrials.gov
BACKGROUND: There is a reported global decrease in the number of clinical trials conducted in recent years. We aimed to determine if this declining trend can be extrapolated to dermatologic clinical t...
Read MoreCharacterization and Assessment of Nanoencapsulated Sanguinarine Chloride as a Potential Treatment for Melanoma
Sanguinarine has a history of use in both folk medicine and early dermatology for the treatment of cutaneous neoplasms. Applied indiscriminately, bloodroot is an escharotic agent with potential to cau...
Read MoreThe Role of the Cutaneous Microbiome in Skin Cancer: Lessons Learned from the Gut
The human microbiome has recently gained prominence as a major factor in health and disease. Here we review the literature regarding the microbiome and cancer and suggest how the microbiome may be man...
Read MoreSafe and Efficacious Use of Intralesional Steroids for the Treatment of Focally Resistant Mycosis Fungoides
Cutaneous T-cell lymphoma is a cancer of skin-homing T cells, of which mycosis fungoides (MF) is the most common variant. MF treatments range from topical steroids to systemic chemotherapy. Resistant ...
Read MoreBimatoprost-Induced Chemical Blepharoplasty
We report significant changes in the appearance of the periorbital area, beyond eyelash enhancement, induced by the topical application of bimatoprost ophthalmic solution, 0.03% (Latisse®, Allerga...
Read MoreSteroid-Free Over-the-Counter Eczema Skin Care Formulations Reduce Risk of Flare, Prolong Time to Flare, and Reduce Eczema Symptoms in Pediatric Subjects With Atopic Dermatitis
INTRODUCTION: Atopic dermatitis (AD) is a chronic skin condition associated with decreased barrier function resulting in periodic flare-ups of erythematous and pruritic lesions. Guidelines recommend d...
Read MoreCosmetic Complications: Rare and Serious Events Following Botulinum Toxin and Soft Tissue Filler Administration
BACKGROUND: Botulinum toxin (BTX) and soft tissue fillers continue to gain in popularity due to their safety, affordability, quick effects, and short recovery times. With the excellent safety profile ...
Read MoreManagement of Onychomycosis and Co-Existing Tinea Pedis
Onychomycosis is a common infection of the nail that often co-exists with tinea pedis. Surveys have suggested the diseases co-exist in at least one third of patients, although actual numbers may be a ...
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Features
Infantile Hemangiomas
Resident Rounds Part I: Program Spotlight: Department of Dermatology, Columbia University Medical Center
Resident Rounds is a section of the JDD dedicated to highlighting various dermatology departments with residency training programs. Resident Rounds includes 3 sections: (1) a program spotlight highli...
Read MoreAnesthetic Blister Induction to Identify Biopsy Site Prior to Mohs Surgery
BACKGROUND: Wrong-site surgery in dermatology often occurs due to difficulty finding the initial biopsy site prior to Mohs surgery. Patients frequently present for Mohs surgery weeks to months followi...
Read MoreResident Rounds Part II: Dermatoses of Pregnancy
Leprosy Masquerading as Rheumatoid Arthritis
Resident Rounds Part III: Case Report: Fatal Cryptococcal Panniculitis in a Lung Transplant Recipient
Cryptococcal panniculitis is a rare entity previously reported in only 13 solid organ transplant (SOT) recipients. Cutaneous cryptococcosis in SOT recipients warrants extensive systemic workup and tre...
Read MoreBefore OR After: Is There a Connection Between the Use of Adjunctive Nonmelanoma Skin Cancer Treatments and Subsequent Invasive Tumors?
Although the therapeutic gold standard for basal cell carcinomas (BCCs) is surgical excision, imiquimod, fluorouracil cream, and photodynamic therapy are frequently used. All 3 modalities have been sh...
Read MorePipeline Previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
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Case Reports
Report of a Case of a Dermatophytoma Successfully Treated With Topical Efinaconazole 10% Solution
Onychomycosis is a common fungal infection of the nail unit that results in discoloration, subungual debris, thickening, onycholysis, and often pain and impairment of mobility. Dermatophytomas are cha...
Read MoreA Case of Multiple Atypical Nevi With Co-Localized Basal Cell Carcinomas on the Scalp: Insight into the Pathogenesis
The authors report a case of a 29-year-old female with multiple lesions on the scalp containing an atypical nevus and a co-localized basal cell carcinoma (BCC) in the same specimen. This is the first...
Read MoreCutaneous Manifestations of Vemurafenib Therapy for Metastatic Melanoma
Vemurafenib, a BRAF inhibitor, is FDA-approved for the treatment of metastatic melanoma in patients who harbor the BRAF V600E mutation. By inhibiting BRAF, vemurafenib prevents the mitogen-activated ...
Read MorePrimary Cutaneous T-cell Lymphoma With Aberrant CD-20 Expression
IMPORTANCE: Primary cutaneous T-cell lymphoma with aberrant expression of cluster of differentiation (CD) 20 is an exceedingly rare manifestation of cutaneous T-cell lymphoma that is easily misdiagnos...
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