Issue Archive
November 2014 | Volume 13 | Issue 11
Original Articles
Long-Term Safety of Ivermectin 1% Cream vs Azelaic Acid 15% Gel in Treating Inflammatory Lesions of Rosacea: Results of Two 40-Week Controlled, Investigator-Blinded Trials
Papulopustular rosacea (PPR) is characterized by facial erythema and inflammatory lesions believed to be primarily caused by dysregulation of the innate immune system. More recent evidence also sugges...
Read MoreTransungual Delivery of Efinaconazole: Its Deposition in the Nail of Onychomycosis Patients and In Vitro Fungicidal Activity in Human Nails
BACKGROUND: Effective transungual delivery of topical antifungal agents in onychomycosis has been hampered by poor nail permeation. To be effective they must have antifungal efficacy, and effectively ...
Read MoreAccess of Efinaconazole Topical Solution, 10%, to the Infection Site by Spreading Through the Subungual Space
OBJECTIVE: To evaluate the ability of efinaconazole vehicle to reach the site of toenail onychomycosis by spreading through the subungual space between the nail plate and nail bed. Lacquer-based vehic...
Read MoreA Single-Blinded Randomized Controlled Study to Assess the Efficacy of Twice Daily Application of Sinecatechins 15% Ointment When Used Sequentially With Cryotherapy in the Treatment of External Genital Warts
OBJECTIVE: To evaluate the efficacy of sequential therapy of cryotherapy and sinecatechins 15% ointment BID versus cryotherapy alone in treatment of external genital warts (EGW).
METHODS: Forty...
Read MoreNonablative 1927 nm Fractional Resurfacing for the Treatment of Facial Photopigmentation
BACKGROUND: Long-term exposure to sunlight, including ultraviolet A and B, produces signs associated with photoaging and photodamage, including laxity and discoloration of the skin. Initial laser trea...
Read MoreClinical Evaluation of a Non-Ablative 1940 nm Fractional Laser
BACKGROUND AND OBJECTIVES: Non-ablative fractional lasers cause little down-time, however, some patients want more noticeable results with fewer treatments. The 1940 nm wavelength matches one of the w...
Read MoreRadiofrequency: An Update on Latest Innovations
As the aging population in our society continues to grow, new technologies and procedures promising a more youthful appearance are continuously sought. The utilization of radiofrequency technology rem...
Read MoreA Focused Monopolar Radiofrequency Causes Apoptosis: A Porcine Model
BACKGROUND: The purpose of this study was to demonstrate the effect of monopolar, focused radiofrequency (RF) with embedded cooling on subcutaneous skin structures. Specifically, the study was to prov...
Read MoreHome-Based Wrinkle Reduction Using a Novel Handheld Multisource Phase-Controlled Radiofrequency Device
BACKGROUND: In the last decade, energy-based aesthetic treatments, using light, radiofrequency (RF), and ultrasound, have gained scientific acceptance as safe and efficacious for non-invasive treatmen...
Read MorePulsed Dye Laser Therapy for Molluscum Contagiosum: A Systematic Review
BACKGROUND: Molluscum contagiosum (MC) is a benign contagious viral skin infection that typically resolves without treatment within months. For cases where treatment is recommended or requested, a num...
Read MoreTreatment of Facial Actinic Keratoses With Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) or Ingenol Mebutate 0.015% Gel With and Without Prior Treatment With ALA-PDT
OBJECTIVE: This randomized, 3-group study compared the efficacy and tolerability of 3 treatment modalities for facial actinic keratoses.
METHODS: Twenty-four healthy adult male and female subje...
Read MoreAntibiotic Resistance: Shifting the Paradigm in Topical Acne Treatment
INTRODUCTION: Multiple topical therapies are available for mild to moderate acne vulgaris. The role of antibiotics and their resistance in the treatment of acne was reviewed by an expert panel of derm...
Read MoreMicrobiome of Affected and Unaffected Skin of Patients With Atopic Dermatitis Before and After Emollient Treatment
Atopic dermatitis (AD) is a chronic inflammatory skin disorder that results in areas of dry, itchy skin. Several cultivation-dependent and –independent studies have identified changes in the co...
Read MoreReal-Life Treatment Profile of Calcipotriene and Betamethasone Dipropionate Topical Suspension in Patients With Psoriasis Vulgaris
BACKGROUND: Treatment with calcipotriene plus betamethasone dipropionate (CBD) fixed-combination topical suspension has been shown to be effective and well tolerated in patients with psoriasis vulgari...
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Features
Ultrasound Technologies for Dermatologic Applications
Update on Male Pattern Hair Loss
VISIA System: A Possible Tool in the Cosmetic Practice
BACKGROUND: Dyspigmentation is a common complaint in the dermatology office.
OBJECTIVE: We also sought to evaluate whether the VISIA Complexion Analysis System (Canfield Imaging Systems, Fairfi...
Read MoreMuscle Weakness in Treatment of Palmar Hyperhidrosis With Botulinum Toxin Type A: Can It Be Prevented?
BACKGROUND: Palmar hyperhidrosis is a chronic disorder, resistant to conventional treatment. Clinical studies suggest the effectiveness of botulinum toxin A in the treatment of primary palmar hyperhid...
Read MoreNews, Views & Reviews. Repurposing of Drugs for Dermatologic Applications: Five Key Medications
Pipeline Previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from th...
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Case Reports
Efficacy of Botulinum Neurotoxin Type A for Treating Recalcitrant Plaque Psoriasis
Use of botulinum neurotoxin A (BoNTA) for treating inflammatory skin disease is an underexplored area in medical dermatology. Preclinical mouse studies have demonstrated efficacy of abobotulinumtoxinA...
Read MoreA Case of New Onset Keratosis Pilaris After Discontinuation of Erlotinib
IMPORTANCE: Keratosis pilaris and keratosis pilaris-like eruptions have been reported in association with RAF inhibitors sorafenib and vemurafenib. We describe herein what is to our knowledge the firs...
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