Issue Archive
May 2014 | Volume 13 | Issue 5
Original Articles
A Retrospective Comparison Between Preoperative and Postoperative Breslow Depth in Primary Cutaneous Melanoma: How Preoperative Shave Biopsies Affect Surgical Management
BACKGROUND: Accurate histopathologic staging of preoperative biopsy specimens is critical for determining optimal surgical management for patients with primary cutaneous melanoma. The American Academy...
Read MoreReview of the Use of a Semisynthetic Bilaminar Skin Substitute in Dermatology and a Case Series Report of Its Utility in Mohs Surgery
Biobrane is a biosynthetic wound dressing that has been widely used in burn treatment and as a skin graft donor site dressing. Our aim for this review was to establish whether Biobrane serves as a use...
Read MoreTrends in the Outpatient Medication Management of Lupus Erythematosus in the United States
BACKGROUND: Systemic lupus erythematosus (SLE) and chronic cutaneous lupus (CCLE) therapy has changed little over the past 50 years. In March 2011, the US Food and Drug Administration (FDA) approved b...
Read MoreAnalysis of Body Regions and Components of PASI Scores During Adalimumab or Methotrexate Treatment for Patients With Moderate-to-Severe Psoriasis
BACKGROUND: The PASI score, the most common outcome measure in clinical trials of psoriasis treatment, is a non-linear scale that does not allow reliable assessment of subtle variations of its compone...
Read MoreUpdate on the Immunological Mechanism of Action Behind Phototherapy
Phototherapy is often used to treat inflammatory skin conditions such as psoriasis and eczema. Much progress has recently been made in understanding the mechanisms underlying the local, cutaneous immu...
Read MoreEffect of Prophylactic Antibiotics on Polyacrylamide Gel Safety in Facial Augmentation
BACKGROUND: Polyacrylamide hydrogel has in the last decade gained popularity as an injectable filler for facial augmentation due to its features of non-toxicity, biocompatibility, safety profile, and ...
Read MoreAn Immunohistochemical Panel to Assess Ultraviolet Radiation-Associated Oxidative Skin Injury
Ultraviolet (UV) radiation results in a significant loss in years of healthy life, approximately 1.5 million disability-adjusted life years (DALYs), and is associated with greater than 60,000 deaths a...
Read MoreA Study to Assess the Occlusivity and Moisturization Potential of Three Topical Corticosteroid Products Using the Skin Trauma After Razor Shaving (STARS) Bioassay
Dysfunction of the epidermal barrier is generally considered a precursor of cutaneous inflammation that can directly contribute to the pathogenesis of skin diseases, notably atopic dermatitis (AD). We...
Read MoreVemurafenib-Related Cutaneous Side Effects Ameliorated by Acitretin
BACKGROUND: Vemurafenib is a BRAF kinase inhibitor that improves the survival of patients with metastatic melanoma, who have the V600E BRAF mutation. The development of cutaneous neoplasms, including ...
Read MoreSteroid-Free Emollient Formulations Reduce Symptoms of Eczema and Improve Quality of Life
Two over-the-counter products have been clinically tested for efficacy and tolerability in the treatment of atopic dermatitis. Study 1 evaluated a daily maintenance Body Cream (Eucerin Eczema Relief B...
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Features
Heads Up for Scalp Melanoma
Defining Locally Advanced Basal Cell Carcinoma
Two Recent JDD Articles Highlight Genome and Proteome Protection and Repair Strategies
Modified Instrument Tie for Surgical Wound Closure
Simplifying surgical technique, increasing safety, avoiding contamination, and decreasing the time to perform a procedure are desirable goals of any procedure. While the basic premise of the instrumen...
Read MoreResident Rounds Part I. The State University of New York Downstate Medical Center Dermatology Residency Training Program
Resident Rounds is a section of the JDD dedicated to highlighting various dermatology departments with residency training programs. Resident Rounds includes three sections: (1) a program spotlight hi...
Read MoreResident Rounds Part II: Useful Immunohistochemical Stains for Differentiating Various Skin Conditions
Resident Rounds Part III: Scleromyxedema: A Rare Disorder Associated With a Monoclonal Gammopathy
Scleromyxedema is a rare primary cutaneous mucinosis affecting middle-aged adults. It is characterized by dermal mucin deposition with increased collagen in the skin and internal organs. We report a ...
Read MoreNews, Views, & Reviews. Antimicrobial Photodynamic Therapy: Applications Beyond Skin Cancer
Pipeline Previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from th...
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Case Reports
Multidisciplinary Management of Advanced Basal Cell Carcinoma: Report of Four Cases
BACKGROUND: Advanced basal cell carcinomas (BCC) are neoplasms with high-risk clinical characteristics that can develop as locally advanced disease or metastasis. Treatment of advanced BCC may result ...
Read MoreParaneoplastic Pityriasis Rubra Pilaris as the Presenting Manifestation of Metastatic Squamous Cell Carcinoma
Pityriasis rubra pilaris (PRP) is a rare idiopathic papulosquamous eruption. Few cases of PRP have been reported in association with malignancies. We report a case of an 83-year-old Caucasian male who...
Read MoreSuperior Vena Cava Obstruction Associated With Nephrogenic Systemic Fibrosis
A 56-year-old woman with hypertension-induced end stage renal disease presented with skin thickening and mottled discoloration. Cutaneous biopsy showed increased dermal fibroblasts embedded in fibromy...
Read MorePapulonodular Mucinosis in a Patient With Systemic Lupus Erythematosus and Antiphospholipid Syndrome
The skin is one of the target organs most commonly affected in lupus erythematosus (LE) and a wide range of cutaneous changes have been described in LE patients. Papulonodular mucinosis (PNM) in parti...
Read MoreSolitary Necrobiotic Xanthogranuloma of an Upper Extremity in Association With Multiple Myeloma
Necrobiotic xanthogranuloma (NXG) is an uncommon granulomatous disorder of unknown pathogenesis that often presents with yellowish plaques in a periorbital distribution. While a majority of cases are ...
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