Issue Archive
September 2012 | Volume 11 | Issue 9
Editorials
Identifying Natural Ingredients and Their Use in Skin Care
This CME supplement reviews the science behind a select group of natural ingredients in the context of treating cosmetic and medical conditions. Dr. Magdalene A. Dohil discusses the data supporting ce...
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Original Articles
Systemic Antioxidants and Skin Health
Most dermatologists agree that antioxidants help fight free radical damage and can help maintain healthy skin. They do so by affecting intracellular signaling pathways involved in skin damage and prot...
Read MoreMicrodermabrasion: Molecular Mechanisms Unraveled, Part 1
Microdermabrasion (MDA) remains a common in-office procedure for many dermatologic practices.The procedure offers minimal downtime with a low incidence of side effects, making it a relatively desirab...
Read MoreMicrodermabrasion: Molecular Mechanisms Unraveled, Part 2
Microdermabrasion (MDA) remains a common in-office procedure for many dermatologic practices. The procedure offers minimal downtime with a low incidence of side effects, making it a relatively desirab...
Read MoreFive-Year Retrospective Review of Safety, Injected Volumes, and Longevity of the Hyaluronic Acid Belotero Basic for Facial Treatments in 317 Patients
Background: Hyaluronic acids (HA) fillers abound in the European community, many with different names in different countries. One such HA is Belotero Basic, recently approved by the FDA in the United ...
Read MoreIs White Coat Hypertension a Concern in Mohs Micrographic Surgery?
Objective: To examine white coat hypertension (WCHTN) in patients presenting for Mohs micrographic surgery (MMS) to determine whether it should be a concern.
Methods:In this prospective study, b...
Read MoreHistologic Improvement in Photodamage After 12 Months of Treatment With Tretinoin Emollient Cream (0.02%)
Background and Objective: Topical retinoids, such as tretinoin, have been established as the gold standard for the treatment of photodamaged skin. This was a single-center, open-label, single-group, ...
Read MoreEffects of Oral Isotretinoin on Serum Folic Acid Levels
Objective: Acne vulgaris is one of the most common skin disorders, and oral isotretinoin has widely been used as a treatment for severe and resistant cases in recent years. This article considers the ...
Read MoreConsideration of Muscle Mass in Glabellar Line Treatment With Botulinum Toxin Type A
The introduction of botulinum neurotoxin type A (BoNTA) for the treatment of glabellar lines marked a revolution in aesthetic medicine, allowing for noninvasive facial rejuvenation and sculpting. Trea...
Read MoreTopical Pimecrolimus 1% Reverses Long-term Suberythemal Ultraviolet B—induced Epidermal Langerhans Cell Reduction and Morphologic Changes in Mice
Objective: Some literature reported that topical calcineurin inhibitors (TCIs) did not accelerate photocarcinogenesis in hairless mice after long-term simulated solar radiation. In this work, we inves...
Read MoreThe “Skinny”on Sculptra: A Practical Primer to Volumization With Poly-L-Lactic Acid
Poly-L-lactic acid (PLLA) is a biostimulatory agent that can correct bony and soft tissue facial deficiencies by producing gradual volume restoration. Proper patient selection and clear expectations a...
Read MoreDelay Techniques for Local Flaps in Dermatologic Surgery
Local flaps may be required to reconstruct defects on the face, neck, and scalp. Occasionally, delay techniques are indicated to reduce the risk for flap ischemia and subsequent necrosis. Delay may be...
Read MoreSafety of Dermal Fillers
Facial wrinkles are the most visible morphological change of the aging process. Therefore, several rejuvenation methods have been developed to cure these unloved signs of the times, such as botulinum ...
Read MoreThe Basic Science of Dermal Fillers: Past and Present Part I: Background and Mechanisms of Action
Dermal fillers have provided a safe and effective means for aesthetic soft tissue augmentation, and have experienced a dramatic increase in popularity during the past 10 years. Much focus has been pla...
Read MoreThe Duke Dermatology Residency Training Program
Resident Rounds is a section of the JDD dedicated to highlighting various dermatology departments with residency training programs. Resident Rounds includes three sections: (1) a program spotlight, h...
Read MoreThe Basic Science of Dermal Fillers: Past and Present Part II: Adverse Effects
The ideal dermal filler should offer long-lasting aesthetic improvement with a minimal side-effect profile. It should be biocompatible and stable within the injection site, with the risk of only trans...
Read MoreCheek Augmentation Improves Feelings of Facial Attractiveness
Objective: Aesthetic fillers aim to rejuvenate the aging face, but the true end goal is to help patients feel better about their appearance. Cheek augmentation seems to elicit immediate recognition of...
Read MoreAdverse Cutaneous Reactions to Chemotherapy Agents
Six Steps to the “Perfect” Lip
Full lips have always been associated with youth and beauty. Because of this, lip enhancement is one of the most frequently requested procedures in a cosmetic practice. For novice injectors, we recom...
Read MoreAn International Perspective on Fillers in Dermatology—From an American Perspective
This manuscript is intended to give one an international perspective on the use of fillers around the world—what makes some of them special and what is the need and what is the purpose of having...
Read MoreGriscelli Syndrome Associated With Hemophagocytic Lymphohistiocytosis
Brighter Eyes: Combined Upper Cheek and Tear Trough Augmentation: A Systematic Approach Utilizing Two Complementary Hyaluronic Acid Fillers
Non-surgical rejuvenation of the periorbital-cheek complex can be effectively and safely accomplished using a combination of two hyaluronic acid (HA) fillers with distinct viscosities. We present a se...
Read MoreNEWS, VIEWS, & REVIEWS
Radiation Dermatitis: Current Perspectives and Future DirectionsFiller Injections With the Blunt-Tip Microcannula
Background:Microcannulas with blunt tips for filler injections have recently been developed for use with dermal fillers. Their utility, ease of use, cosmetic outcomes, perceived pain, and satisfaction...
Read MorePIPELINE PREVIEWS
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
Read MoreAdjunctive Use of a Facial Moisturizer SPF 30 Containing Ceramide Precursor Improves Tolerability of Topical Tretinoin 0.05%: A Randomized, Investigator-Blinded, Split-Face Study
Objectives: To assess the benefit of adjunctive use of a SPF 30 moisturizing lotion in reducing local side effects associated with atopical tretinoin cream.
Methods:This was a randomized, invest...
Read MoreCLINICAL TRIAL REVIEW
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
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Features
Case Reports
In Vivo Reflectance Confocal Microscopy Features of Discoid Lupus Erythematosus
Background: Discoid lupus erythematosus (DLE) is an inflammatory condition characterized by round demarcated lesions with varying amounts of erythema, telangiectasia, scaling, follicular plugging, dy...
Read MoreAntiphospholipid Antibody Syndrome Secondary to Trimethoprim/Sulfamethoxazole
Antiphospholipid antibody syndrome (APS) results from autoantibodies to cell surface phospholipids or phospholipid-binding proteins resulting in clotting anomalies and can have devastating sequelae, i...
Read MoreA Pathergic Response to Fractional CO2
Pathergy is a nonspecific response to stimuli seen in a multitude of disease states. We present what we feel is a unique variant of this phenomenon, a case of multiple keratoacanthomas developing foll...
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