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Comparative Efficacy of Intralesional Steroid Injections vs Cryotherapy for the Treatment of Alopecia Areata

By February 28, 2025No Comments
Journal of Drugs in Dermatology JDD Article About Comparative Efficacy of Intralesional Steroid Injections vs Cryotherapy for the Treatment of Alopecia Areata

Intralesional Steroids vs. Cryotherapy: Which Wins for Alopecia Areata?

Alopecia Areata (AA) remains an enigmatic condition with treatment options offering varying degrees of success. While intralesional corticosteroids are the first-line treatment, could cryotherapy offer a viable alternative?

A recent study published in JDD compared intralesional triamcinolone acetate to cryotherapy with liquid nitrogen over six months in 118 patients. The results? Intralesional steroids demonstrated significantly higher efficacy (83.05%) compared to cryotherapy (50.85%) (P=0.0001).

For dermatologists seeking the most effective treatment approach for AA, this study underscores the continued dominance of injectable steroids. But could cryotherapy still have a niche role in treatment-resistant cases? Read the full study for key insights.