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Atopic Dermatitis
Articles
Cross-Sectional Study of Psoriasis, Atopic Dermatitis, Rosacea, and Alopecia Areata Suggests Association With Cardiovascular Diseases
Background: A growing body of evidence suggests that several inflammatory skin diseases (ISDs) are associated with systemic inflammation and cardiovascular disease (CVDs).
Sequential Treatment With Topical Trifarotene and Injectable NASHA Gel in Acne Scars: A Case Series
Background: Topical retinoids are a mainstay in acne management and have been shown to improve skin texture. Injectable non-animal stabilized hyaluronic acid (NASHATM) gel as skin booster is largely used in aesthetic treatments to improve skin quality including the appearance of atrophic acne scars.
A Qualitative Study on Product's Impact on Atopic Dermatitis Among Adolescent and Adult Patients
Objective: To qualitatively assess the life experiences and impact of treatment in adult and adolescent patients with AD being treated with this product.
The Safety and Efficacy of Roflumilast Cream 0.15% and 0.05% in Patients With Atopic Dermatitis: Randomized, Double-Blind, Phase 2 Proof of Concept Study
Background: Patients with atopic dermatitis (AD) need safe and effective topical treatments.
Objective: To assess safety and efficacy of a specific cream in patients with mild to moderate AD.
Analysis of Reddit Reveals Dupilumab Questions Among Atopic Dermatitis Patients
Atopic dermatitis patients are turning to social media to seek guidance and source medical information. Reddit, the seventh most visited website in the US, contains the popular “eczeMABs” subreddit, a forum dedicated to discussing monoclonal antibody therapy for atopic dermatitis.
Patient Questions about Atopic Dermatitis from Reddit
Atopic dermatitis and eczema patient questions remain unanswered as they turn to Reddit. Reddit, the seventh most visited website in the US with approximately 430 million monthly active users, has become a popular platform for patients to source medical information and discuss diseases. See their questions, frustrations and insights.
The Heterogeneity of Atopic Dermatitis
Atopic dermatitis (AD) is a chronic and burdensome inflammatory skin disease. This narrow and overly simplified description overlooks the heterogeneity of AD. While itch is the most prevalent and burdensome symptom of AD,skin-pain is one of several other symptoms that contribute to disease-burden.
Topical S. aureus – Targeting Endolysin Significantly Improves Symptoms and QoL in Individuals With Atopic Dermatitis
Atopic dermatitis (AD) is a chronic skin condition affecting an increasing number of children and adults whose quality of life is impacted by chronic itch and pain. It is characterized by an altered epidermal barrier, skin inflammation, and skin microbiome dysbiosis particularly over-colonization of Staphylococcus aureus.
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Case Reports
Pustular Psoriasis Appearing Induced by Therapy in a Patient With Atopic Dermatitis
A treatment inhibits T-helper 2 (Th2)-driven inflammation cascade by blocking interleukin-4 (IL-4) and IL-13 signaling, which has been recognized to play a crucial role in the pathogenesis of atopic dermatitis (AD) and shown encouraging efficacy on moderate to severe AD.1 We report an interesting Chinese AD case, which developed into pustular psoriasis after treatment.
Treatment for Prurigo Nodularis and Pruritis
Prurigo nodularis (PN) is a disease in which chronic scratching and picking of the skin due to intense pruritis results in papulonodules, notably in areas that are accessible to the patient. The pathophysiology is hypothesized to be mediated by a Th2 helper cell response, similar to that seen in atopic dermatitis, therefore, treatment of PN would be expected to elicit a therapeutic response.
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Translational Lecture Series
Targeting cAMP Signaling for the Treatment of Inflammatory Diseases of the Skin
Dr. Jon Zippin, Assistant Attending Dermatologist and Assistant Professor of Dermatology at Weill Medical College of Cornell, elucidates the complexity of cAMP biology and the translational impact of PDE4 inhibition as it relates to chronic inflammatory skin diseases. Tune in to learn why targeting this pathway is clinically meaningful but also where more work is needed to improve outcomes.
Update on Pediatric Inflammatory Skin Disorders: How Pathogenesis Informs Treatment
Dr. Amy Paller, Walter J. Hamlin Professor and Chair of Dermatology & Professor of Pediatrics at Northwestern University Feinberg School of Medicine in Chicago, Illinois, delivers a presentation discussing the cause and treatment of pediatric Atopic Dematitis, including co-morbidities, epidermal barrier impairment, and compliance issues.
Itch form Bedside to Bench
Dr. Gil Yosipovitch, Professor of Dermatology at University of Miami Miller School of Medicine, provides residents and physicians access to the latest bench research and practical pearls from a master in pruritus that will help them offer the highest quality evidence-based dermatological care.
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Podcast Episodes
Special Considerations for Managing Eczema in the Elderly
Atopic dermatitis does not discriminate. The second most common inflammatory skin disease (coming for you, acne vulgaris) can be appreciated across all demographics which contributes to the insane heterogeneity about which we are commonly taught. Unique considerations and approaches must be employed to ensure a personalized approach. Join Dr. Katrina Abuabara, Associate Professor of Epidemiology and Dermatology at UCSF, as she reviews her approach to caring for the geriatric AD population and their caregivers with JDD Podcast host Dr. Adam Friedman. This topic never gets old!
This podcast series is supported by Pfizer.
Don’t Fear, Getting Involved with NEA is Oh So Clear
Cutting the cord for residency training can feel like losing one’s Netflix account, distanced from the epicenter of cultural or dermatologic life. How to stay engaged, involved, or even keep your finger on the rapid pulse of innovation or development you ask? It’s as simple as sending an email. JDD Podcast host Dr. Adam Friedman takes a deep dive with National Eczema Association (NEA) Vice President of Scientific and Clinical Affairs Wendy Smith-Begolka on all paths to engagement. Education, research, community advocacy…it’s all there and a 5 gm sample tube throw away (meaning real close). Tune in to learn how to continue the cutaneous connection.
This podcast series is supported by Pfizer.
Atopic Dermatitis Treatment – The Future Landscape
Hall of famers Dr.s Amy Paller and Jonathan Silverberg join host Dr. Adam Friedman to review current moderate to severe AD treatment approaches and use of systemic therapies, discuss advancement on AD clinical management with use of novel target therapy, and share clinical experience with the use of biologics treatment. As we have all been thrown a curve ball in life, faculty address the growing concerns surrounding dermatology-related immunosuppressant therapy during the pandemic and how to discuss this issue with patients. Slide into home with a peak at the future therapies landscape in clinical development.
Perspectives on Managing Moderate-to-Severe Atopic Dermatitis
Join host Dr. Adam Friedman in this Atopic Dermatitis dedicated series as he parties with and picks the brains of dermatology powerhouses Dr.s April Armstrong and Lawrence Eichenfield on pursuing a practical and powerful process to partner with patients of all ages and partake in a long standing management strategy.
Insights On the Pediatric, Adolescent & Adult AD Patient
Dr. Adam Friedman is joined by Dr. Lindsey Finklea, a practicing dermatologist and parent/caregiver of a child with severe atopic dermatitis, and Dr. Peter Lio, podcast veteran and AD focused Derm extraordinaire, to discuss the issues affecting patient-family/patient-caregiver interactions and offer clinical pearls for effective management strategies to best assist the needs of parents, families and caregivers for patients with the AD.
Current Understanding of the Pathophysiology, Etiology, Prevalence & Burden of AD
Dr. Adam Friedman is joined by the dynamic dermatitis duo Dr. Anna De Benedetto, Associate Professor of Dermatology at the University of Florida, and Dr. Eric Simpson, Professor of Dermatology at the School of Medicine at Oregon Health & Science University, to dissect established and emerging pathophysiologic details of this dastardly dermatitis.
Supplements
Management of Atopic Dermatitis
The treatment horizon for pediatric AD is encouraging. Newer pharmaceuticals are now joined by novel formulations of established medications, which arms dermatologists with an increasing array of treatments to tackle this challenging condition.
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Next Steps in Derm
Sleep Like a Baby: Integrative Tips for Sleep in Atopic Dermatitis
Sleep is essential for our overall well-being and one of the pillars of atopic dermatitis management. Unfortunately, we don’t learn or talk about this much in dermatology. Don’t fret- Dr. Vivian Shi shares her integrative strategies for optimizing sleep in atopic dermatitis!
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Controversies in Pediatric Dermatology: Systemic Therapies
Dr. Yasmine Kirkorian, Interim Chief of Dermatology at Children’s National Health System and Assistant Professor of Dermatology and Pediatrics at the George Washington School of Medicine & Health Sciences, summarizes recent controversies in the field of pediatric dermatology regarding the usage of systemic therapies in children.
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