Supplement Individual Article: Pediatric Acne Patients’ Treatment Real-World Case Series Using Skincare as Monotherapy, Adjunctive, and Maintenance Treatment
February 2023 | Volume 22 | Issue 2 | SF376527s3 | Copyright © February 2023
Published online January 31, 2023
Lawrence A. Schachner MD FAAD FAAP,a Anneke Andriessen PhD,b Latanya Benjamin MD FAAD FAAP,c Madelyn Dones MD FAAP,d Ayleen Pinera-Llano MD FAAP,e Linda Keller MD FAAP,f Leon Kircik MD FAAD,g Adelaide A. Hebert MD FAADh
aDivision of Pediatric Dermatology, Department of Dermatology and Cutaneous Surgery, Department of Pediatrics, Leonard M. Miller School of Medicine, University of Miami, FL
bRadboud UMC, Nijmegen and Andriessen Consultants, Malden, The Netherlands
cDepartment of Women's and Children's Health, Florida Atlantic University, Boca Raton, FL
dBaptist Health Hospital, Nicklaus Childrens' Hosptital, Miami, FL
eKing Bay Pediatrics, Maimi, FL, General Pediatrics, Nicklaus Children's Hospital, Miami, FL
fBaptist Health Baptist Hospital, Baptist Health South Miami Hospital, Miami, FL
gIcahn School of Medicine at Mount Sinai, New York, NY; Indiana University Medical Center, Indianapolis, IN; Physicians Skin Care, PLLC Louisville, KY; DermResearch, PLLC Louisville, KY; Skin Sciences, PLLC Louisville, KY
hDepartment of Dermatology and Pediatrics, McGovern Medical School, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX
Abstract
Background: Pediatric acne is a common, complex, multifactorial inflammatory skin disease with various expressions in childhood that can be categorized by age, severity, and pubertal status. A pediatric acne case series is presented to educate health care providers treating children with acne to tailor acne prescription, nonprescription acne therapy, skin care, and maintenance treatment to improve patient outcomes.
Methods: A panel of 8 advisors in pediatric dermatology, dermatology, and pediatrics who treat pediatric patients with acne reported on clinical cases from their practice. During the meeting, the advisors discussed 17 pediatric acne cases and agreed to select 8 cases covering various presentations of pediatric acne, patient ages, and skin types. The case series gives a logical flow from youngest to oldest pediatric patients with acne.
Results: The 8 cases covered neonatal acne: birth to ≤8 weeks; preadolescent acne: ≥7 to 12 years; and adolescent acne: ≥12 to 19 years or after menarche for girls. It is to be noted that acne eruptions in children ages 1 to 6 years old are unusual and often associated with underlying endocrine and tumor issues. They are not included in this work. The advisors discussed why they selected the case, previous treatment, type of prevention and education provided, skin care as mono or adjunctive treatment, prescription and nonprescription therapy and maintenance treatment, key takeaways, and clinical pearls from the case. Skincare products containing lipids such as ceramides promote a healthy skin barrier in acne monotherapy, adjunctive, and maintenance treatment. However, their role in pediatric acne is not well defined and requires more studies.
Conclusion: Sharing best practices in acne therapy and maintenance treatment for pediatric patients with acne may support health care providers treating children to improve clinical outcomes.
J Drugs Dermatol. 2023;22:2(Suppl):s3-14.
INTRODUCTION
Acne vulgaris (acne) is a multifactorial inflammatory chronic skin disease with a prolonged course of acute outbreaks, relapses, and recurrences with significant social, psychological, and physical consequences.1-6 The expressions of pediatric acne depend on age (neonatal, infantile, mid-childhood, preadolescent, and adolescent), severity (mild, moderate, severe), type (eg, comedonal, papules, pustules, nodular), and other characteristics (eg, oily skin, pomade acne).5-8 Post-inflammatory hyperpigmentation (PIH) and scar formation may occur in some patients making it necessary to initiate timely and effective treatment.9,10
